Fully integrated real time multi-wavelength photoacoustics for early disease detection (FULLPHASE)

FullphaseLogo The objective of FULLPHASE is the transition of PA imaging from a lab-based technique to a low-cost portable multi wavelength combined PA and US system. In order to reach that goal, the FULLPHASE partners offer specific expertise over complementary backgrounds in diode laser technology, laser beam shaping, ultrasound imaging technology, and system integration. The impact of the FULLPHASE system will be shown in oncology, rheumatology and cardio vascular disease.


FULLPHASE will integrate different scientific and technological expertise, for point-of-care early diagnosis, by means of specific knowledge, which will be directed towards:

  • Multi wavelength diode laser beam sources with very high pulse powers (QUANTEL, OSRAM).
  • Highly efficient diode laser driver (BrightLoop).
  • Multi-wavelength diffractive optical beam shaping (SILIOS).
  • Optimal light delivery (SILIOS, RUB, UNIBE).
  • PA imaging depth of a few centimetres (RUB, UNIBE).
  • Advanced beam forming and temporal resolution (ESAOTE).
  • Quantitative functional and structural imaging (UTWENTE).
  • In-vitro and ex-vivo verification (UTWENTE, UNIBE, RUB, BMT).
  • Preclinical validation. (UTWENTE, UNIBE, RUB, ZGT)

The project consortium consists of 11 participants from France, Germany, Switzerland, and the Netherlands:

  • Esaote Europe BV, Maastricht (NL)
  • Mira Institute for Biomedical Technology and Technical Medicine, University of Twente, Enschede (NL)
  • Quantel, Paris (FR)
  • Silios Technology (FR)
  • Institute of Applied Physics and University Hospital, University of Berne (CH)
  • Osram Opto Semiconductors GmbH (GER)
  • Ruhr-Universität Bochum, Institute for Medical Engineering (GER)
  • BrightLoop (FR)
  • Biomedical Engineering (BMT), Eindhoven University of Technology TU/e (NL)
  • TP21 GmbH (GER)
  • ZGT Hospital Group Twente (NL)

Official Project Homepage: Fullphase

FULLPHASE is supported by the European Commision's 7th RTD Framework Programme Collaborative Project No. 318067

Project duration: October 2012 - September 2016

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